Table 1.
Enzyme | nmol/h/mg cell protein |
Microglia activity/macrophage activity | |
---|---|---|---|
Macrophage activity | Microglia activity | ||
Tripeptidyl peptidase (TPP) I | 50 | 238 | 4.74 |
Cathepsin B | 56 | 80 | 1.44 |
Dipeptidyl peptidase (DPP) I | 1915 | 7242 | 3.78 |
Cathepsin H | 563 | 472 | 0.84 |
DPP II | 16 | 79 | 5.05 |
Cathepsin D | 51 | 147 | 2.88 |
The assay media were buffered as follows: cathepsin D, pH 3.5; TPP I, pH 4.5; cathepsin B, DPP I and DPP II, pH 5.5; and cathepsin H, pH 6.8.