Table 1.
List of marker genes used to assess lineage development in ES cells
| Gene symbol | Description | Lineage |
|---|---|---|
| Sox17 | SRY-box containing gene 17 | Endoderm |
| PDGFRA | Platelet-derived growth factor receptor, alpha | Endoderm |
| Gata4 | GATA binding protein 4 | Endoderm |
| Gata6 | GATA binding protein 6 | Endoderm |
| Foxa2 | Forkhead box A2 | Endoderm |
| GSC | Goosecoid | Mesendoderm |
| Nodal | Nodal | Mesendoderm |
| MixL1 | Mix1 homeobox-like 1 | Mesendoderm |
| Hand1 | Heart and neural crest derivatives expressed 1 | Mesoderm |
| Nkx2.5 | NK2 transcription factor related, locus 5 | Mesoderm |
| Gata2 | GATA binding protein 2 | Mesoderm |
| Nestin | Nestin | Ectoderm |
| GFAP | Glial fibrillary acidic protein | Ectoderm |
| Pax6 | Paired box gene 6 | Ectoderm |
| TDGF1 | Teratocarcinoma-derived growth factor/Cripto | Ectoderm |
| Sox1 | SRY-box containing gene 1 | Ectoderm |
| REST | RE1-silencing transcription factor | Ectoderm |
| CoREST | REST Co-repressor 1 | Ectoderm |
| FGF5 | Fibroblast growth factor 5 | Ectoderm |
| BMP4 | Bone morphogenetic protein 4 | Trophectoderm |
| CDX2 | Caudal type homeobox 2 | Trophectoderm |
| DKK3 | Dickkopf homolog 3 | Wnt pathway |
| Gsk3beta | Glycogen synthase kinase 3 beta | Wnt pathway |