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. 2007 Mar 30;3(3):e43. doi: 10.1371/journal.pgen.0030043

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© 2007 Yeyati et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Dorsal views shown are: (A) Unilateral anophthalmia; (B) Unilateral microphthalmia; and (C) Unilateral nanophthalmia (UN), illustrating retina (re), lens (le), cornea (co). (D) Ventral view of cyclopic embryo is shown. (E) Bilateral anophthalmia is shown (top, lateral view; bottom, dorsal view). (F) Anterior body-axis duplication (ABD), two complete heads formed; incomplete ABD were also observed (not shown). (G) Posterior body duplication (PBD), two notochords showing adjacent somite boundaries (arrows), culminating in two tails.

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