Figure 1. Generation of animals conditionally misexpressing the Arx gene.

Schematic depicting the targeting vector before (top) and after (bottom) recombination of the 2 LoxP sites induced by the phage P1 Cre recombinase. β-Galactos., β-galactosidase. Inset: Visual examination of representative Cre-negative E10 embryo and adult pancreas under fluorescent light. Original magnification, ×40.