Skip to main content
. Author manuscript; available in PMC: 2008 Feb 20.
Published in final edited form as: Virology. 2006 Sep 29;358(2):391–401. doi: 10.1016/j.virol.2006.08.042

Figure 5.

Figure 5

Helper virus-supported AAV infections alter cell morphology. A549 cells were infected with AAV (100 IU) and/or Ad5 (5 moi) or pm534 (5 moi). Unfixed cells were microscopically examined 3 days pi. Uninfected cells and cells infected with Ad alone are on the top panels, and the corresponding infections with the addition of AAV are below. Cells infected with either Ad5 or pm534 alone were rounded up and enlarged, but cells infected with a helper virus and AAV exhibited cell shrinkage and membrane blebbing. The arrows indicate cells with extensive membrane blebbing. The average area of cells exhibiting cytopathic effect is shown in nm2.