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. Author manuscript; available in PMC: 2008 Feb 1.
Published in final edited form as: Neuropharmacology. 2006 Oct 18;52(2):576–589. doi: 10.1016/j.neuropharm.2006.08.027

Figure 1.

Figure 1

Assessment of thermal hyperalgesia in the CCI model of neuropathic pain. Data are presented as the difference score of ipsilateral/experimental – contralateral/control hind paw withdrawal latency in seconds. Each point is expressed as the mean ± S.E.M. (number of rats in parentheses). Statistical significance different from sham-operated rats was reached at * p < 0.01, ** p < 0.001 using a Student’s t-test. Thermal pain perception peaks at days-2-8 post-CCI, with a steady decline to non-significant differences from sham-operated rats beginning at day-14 post-CCI. CCI = chronic constriction injury.