Table 3.
Leukocyte receptors, their corresponding ligands, and their allowed behaviors
Leukocyte Receptor | Surface Receptor-Ligand | Behaviors |
PSGL-1 | P-Selectin | Rolling |
VLA-4 Integrin | VCAM-1 | Rolling, Firm Adhesion |
CXCR-2 Chemokine Receptor | GRO-α Chemokine | Activation |
These three receptor-ligand pairs were chosen because together they are sufficient for enabling leukocytes to roll, become activated, and firmly adhere in vitro.