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. 2005 Sep;49(3):158–209.

Table 1.

The meaning of the OCEBM levels of evidence

The interpretation (below) of the meaning of levels of evidence (left column) is the opinion of the GDC, based on the OCEBM recommendation grading system.
Evidence level Study results are … You interpret results … Clinical meaning
1a almost certain objectively Recommendations directly supported by evidence are very likely reliable and valid.
1b
1c
2a strongly suggestive objectively Recommendations directly supported by evidence are likely reliable and valid.
2b
2c
3a
3b
4 suggestive objectively Recommendations directly supported by evidence may be reliable and valid.
5 inconclusive objectively Reliability and validity of recommendations uncertain.
subjective extrapolation from Levels 1–5

Adapted from the OCEBM levels of evidence (May 2001).7 Documents at the referenced web-site were used to discriminate between good and poor quality studies of the same design.