Table 3.
Odd Ratios of Breast Cancer and 95% Confidence Intervalsa Associated with Quintiles of Lipid-Adjusted Serum Levels of DDE and PCBs Among African-American Case Patients and Controls
| Quintile of lipid-adjustedc organochlorine | Cases/Controls | OR (95% CI)a |
|---|---|---|
| PCBs (μg/g)d | ||
| BDLb | 144/136 | 1.0 |
| >0 – 0.38 | 61/49 | 1.06 (0.67, 1.67) |
| >0.38 – 0.47 | 46/47 | 0.82 (0.50, 1.33) |
| >0.47 – 0.60 | 42/47 | 0.76 (0.47, 1.24) |
| >0.60 | 61/47 | 1.01 (0.63, 1.63)
p(trend) = 0.56 |
| DDE (μg/g) | ||
| <=0.44 | 61/67 | 1.0 |
| >0.44 – 0.73 | 62/63 | 0.98 (0.59, 1.62) |
| >0.73 – 1.15 | 76/67 | 1.07 (0.65, 1.75) |
| >1.15 – 1.91 | 81/65 | 1.14 (0.69, 1.88) |
| >1.91 | 75/65 | 1.02 (0.61, 1.72)
p(trend) = 0.74 |
c
Lipid adjustment done as described by Phillips et al.,1989.
b
Below Detectable Limit of Assay
d
1 case and 1 control did not have data on PCB levels
a
Adjustment made for age (35–44 years, 45–54 years and 55–64 years); BMI (<= 24.90 kg/m2, 24.91 – 28.94 kg/m2, 28.95 – 33.65 kg/m2, > 33.65 kg/m2); breastfeeding (continuous variable)