TABLE 5.
Odds ratios (ORs) of prostate cancer according to quartile (Q) of serum selenium stratified by smoking status1
| Quartile of Serum Selenium
|
||||||
|---|---|---|---|---|---|---|
| Smoking status | Q12 (50.5 to < 126.8 ng/mL) | Q2 (≥ 126.8 to < 141.9 ng/mL) | Q3 (≥141.9 to < 158.0 ng/mL) | Q4 (≥158.0 to 253.0 ng/mL) | P for trend3 | P for interaction |
| None | 0.007 | |||||
| Cases/controls (n) | 64/76 | 70/53 | 80/72 | 55/72 | ||
| OR4 | 1.00 | 1.65 | 1.50 | 1.32 | 0.15 | |
| 95% CI | — | 0.95, 2.86 | 0.86, 2.59 | 0.72, 2.40 | ||
| Smokers (current and former) | ||||||
| Cases/controls (n) | 119/123 | 103/142 | 100/127 | 76/135 | ||
| OR4 | 1.00 | 0.70 | 0.91 | 0.65 | 0.09 | |
| 95% CI | — | 0.48, 1.03 | 0.65, 1.35 | 0.44, 0.97 | ||
1
Men smoking pipe or cigar were excluded (57 cases and 79 controls).
2
Reference category.
3
Obtained by using serum selenium as a continuous variable.
4
Obtained from a multivariate conditional logistic regression analysis adjusted for age, time since initial screening, year of blood draw, and study center.