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. Author manuscript; available in PMC: 2008 Feb 1.
Published in final edited form as: Neurobiol Learn Mem. 2006 Oct 16;87(2):264–268. doi: 10.1016/j.nlm.2006.09.002

Figure 1.

Figure 1

Examples of the minimum (black) and maximum (gray) extent of lesions in the retrohippocampal area are represented in the horizontal plane (C). In the right panel in (B), note the intensification of the AChE stain in the outer molecular layer in a rat with a bilateral EC lesion (white arrow), which indicates septodentate sprouting, compared to the AChE stain in a rat with a sham operation shown in the left panel (white arrow). In the right panel in (B), also note the widening of the pale-staining zone of the commissural/associational fiber plexus, which may be taken to indicate the expansion of the commissural/associational inputs to the inner molecular layer (black arrow; West et al., 1982), compared to the pale-staining zone in the left panel (black arrow). The open arrows indicate the upper margin of the dentate supragranular zone. (The photomicrographs in (B) are from the horizontal plane of the dentate gyrus indicated in the box shown in (A) at Bregma –3.1. Illustrations adapted from Paxinos and Watson (1986). White scale bar in right panel of (B) = 60 μm).