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. Author manuscript; available in PMC: 2008 Jan 19.
Published in final edited form as: Brain Res. 2006 Dec 6;1129(1):63–71. doi: 10.1016/j.brainres.2006.09.112

Figure 5.

Figure 5

Chemical synapse formation between specific neurons is network dependent. (A) Schematic and sample traces illustrating one example of synaptogenesis in a 3-cell network: a 5d 19-19 contact possessed strong electrical coupling (solid line in schematic) and no chemical synaptic transmission, while only weak electrical coupling (dashed line) and no chemical synaptic transmission was recorded at the 1d contact of the central 19 and 110 (record traces). Scale bars equal 20mV and 1 sec. (B) By 5 days in culture, the strength of electrical connections between central neuron 19 and neuron 110 had diminished and strong chemical synaptic transmission was present (solid circle head). Strong chemical connections were also formed at the 1d contact between neurons 19 and 110 in this three-cell configuration (record traces). Scale bars equal 20mV and 1 sec.