Figure 3.

Tissue concentrations of unesterified (upper panels) and esterified (lower panels) cholesterol in NPC^+/+/LDLR^+/+, NPC^−/−/LDLR^+/+, and NPC^−/−/LDLR^−/− mice 7 weeks of age. There were 6–10 animals in each group. The asterisk (∗) identifies those values in the NPC^−/−/LDLR^+/+ and NPC^−/−/LDLR^−/− groups that were significantly different from those in the NPC^+/+/LDLR^+/+ animals. The dagger (†) indicates those values in the NPC^−/−/LDLR^−/− mice that were significantly different from those in the NPC^−/−/LDLR^+/+ groups.