Figure 9.—
Predictions of background selection are insensitive to uncertainty in realistic DDME width estimates. For each assumed DDME shape (x-axis), a corresponding estimate of the location parameter was made from the diversity data. The standard gene structure without neighboring genes was assumed, with rg = 2.5 × 10−6. Other features of the curves are as in Figure 3. The bottom three lines belong to the axis on the right. Note that realistic shapes in this case are in the range 20–100, as narrower shapes predict too few lethal mutations and wider shapes predict too many lethal mutations (on the basis of estimates in Loewe and Charlesworth 2006). Details of the assumed DDMEs can be found in Table 1.