Table 1.
CCR5 haplogroup frequencies in different racial and ethnic groups
| Haplogroup | African
|
African American
|
Asian
|
Caucasian
|
Hispanic American
|
|||
|---|---|---|---|---|---|---|---|---|
| Pygmies | Non-pygmies | Uninfected | HIV-1 infected | Uninfected | Uninfected | HIV-1 infected | HIV-1 infected | |
| HHA | 70.6 (34) | 26.5 (49) | 22 (209) | 20.1 (410) | 16.8 (158) | 10.7 (248) | 9.3 (618) | 9.5 (74) |
| HHC | 2.0 (25) | 10.6 (71) | 15.6 (212) | 14.8 (410) | 36.5 (163) | 37.1 (206) | 36.3 (618) | 34.5 (74) |
| HHD | 0 (37) | 20.1 (82) | 18.4 (212) | 20.1 (410) | 4.4 (34) | 0 (429) | 1.0 (618) | 3.4 (74) |
| HHE | 11.8 (38) | 20.7 (58) | 18.4 (193) | 18.7 (410) | 25 (376) | 31.8 (140) | 31.9 (618) | 30.4 (74) |
| HHF*1 | 6.3 (40) | 11.8 (68) | 4.1 (195) | 5.0 (410) | 1.6 (478) | 2.0 (154) | 0.8 (618) | 2.7 (74) |
| HHF*2 | 6.3 (40) | 14.7 (68) | 14.1 (195) | 14.9 (410) | 12.8 (478) | 5.5 (154) | 8.6 (618) | 14.2 (74) |
| HHG*1 | 2.5 (40) | 0.7 (71) | 4.5 (210) | 3.7 (410) | 0.8 (518) | 3.3 (151) | 4.4 (618) | 2.0 (74) |
| HHG*2 | 0 (40) | 0 (71) | 2.6 (210) | 2.3 (410) | 0.1 (518) | 5.6 (151) | 7.7 (618) | 3.4 (74) |
The number in parentheses denotes the number of individuals from whom the haplotype frequency (%) was derived. HHB haplotypes are rare, and their frequencies are not shown. Also, because of failure to amplify by PCR all CCR5 polymorphisms and/or limited DNA quantities, the number of noninfected individuals for whom complete haplotype frequency data are available varies. Hence, for these two reasons the frequencies approximate but do not total to 100%. Individuals in whom a CCR5 haplotype appeared to be a product of a recombination event were excluded from analysis.