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Calcineurin-dependent activation of p38 and p44/42 MAPKs. M1-t-p53 cells were cultured at 37°C with 10 nM TG for various times or without TG (0 min with TG) in the absence (−) or presence (+) of 100 nM CsA. Western blotting was carried out with antibody to p38 or p44/42 MAPKs or to the doubly phosphorylated (Phospho-p38 and Phospho-p44/42) MAPKs.
