Table 2.

Plasma fractional catabolic rates for ¹²⁵I-labeled NMTC/[³H]cholesteryl oleyl ether-labeled HDL in SR-BIatt mice with apoE-deficient background

Mice	125I-labeled NMTC protein, pool/h	[3H]Cholesteryl oleyl ether, pool/h	3H − 125I, pool/h
wt	0.094  ±  0.010	0.141  ±  0.015	0.047  ±  0.014
apoE0	0.068  ±  0.022	0.080  ±  0.029**	0.012  ±  0.012**
SR-BIatt/apoE0	0.070  ±  0.018*	0.068  ±  0.020***	−0.002  ±  0.004**

Blood was collected periodically from four wt, five female apoE0, and seven female apoE0/SR-BIatt mice over 24 h after injection of labeled autologous HDL. The values are means ± SD. The asterisks denote statistical significance: *, P < 0.05; **, P < 0.01; and ***, P < 0.001, respectively, between wt and apoE or apoE0/SR-BIatt by two-tailed Student’s t test for unpaired data.