Table 2.

Relationship between PPT-A genotype and neuronal damage after kainate SE

Damage scores	Hematoxylin & eosin		Cresyl violet
	PPT-A +/+ n = 10	PPT-A −/−n = 6	PPT-A +/+ n = 6	PPT-A −/−n = 3
0	2  (20%)	4  (67%)	2  (33%)	2  (67%)
1	1  (10%)	1  (17%)	0  (0%)	0  (0%)
2	0  (0%)	1  (17%)	0  (0%)	1  (33%)
3	3  (30%)	0  (0%)	1  (17%)	0  (0%)
4	4  (40%)	0  (0%)	3  (50%)	0  (0%)

Neuronal damage or loss were assessed 3 days (hematoxylin & eosin staining) and 7 days (cresyl violet staining) after kainate injection (35 mg/kg). Neuronal damage was scored (13) as follows: 0, no damage; 1, occasional injured neurons in CA1 or CA3; 2, small area (<10%) with neuronal damage or loss in CA1 or CA3; 3, greater area (10–50%) of neuronal damage or loss in CA1 or CA3; 4, extended (>50%) neuronal loss or damage in both CA1 and CA3.