Table 5.
Effect of RS86 on APP levels in rats 12 months after 192 IgG-saporin lesions
Region | Cerebral cortex | Hippocampus | Striatum |
---|---|---|---|
APP, % of lesion control | 88 ± 13 | 53 ± 6* | 71 ± 15 |
Data are presented as mean ± SEM APP OD values in different regions of the brain and are expressed as percentage of APP values in lesioned, vehicle-treated control group. *, P < 0.05, significantly different from vehicle-treated control group (Student’s t test).