Coexpression of nAChR subunits in noradrenergic neurons in the LC. Each bar represents the fraction of cells in the sample that express the subunit or the association of subunits indicated in the label of x axis. The subunit β2 is expressed in all neurons. Significant association of subunits is observed for α6 and β3, α3 and β4, and α3β4 and α5. Significant exclusion of subunits is observed for α7 and α3β4. Significant association (○, P < 5%; ○○, P < 1%) and significant exclusion (∗, P < 5%) are given.