Table 1.

Association Studies of Thrombosis Genes in Ischemic and Carotid Atherosclerosis

Gene	Reference	Polymorphism	Cases, n; controls, n	Results
Factor V	Catto et al., 1995 [56]; Catto et al., 1996 [57]	G1691A	348; 247	Negative
	Kontula et al., 1995 [58]	G1691A	236; 137	Negative
	Ridker et al., 1995 [15]	G1691A	209; 209	Negative
	Martinelli et al., 1997 [59]	G1691A	155; 155	Negative
	Press et al., 1996 [60]	G1691A	116; 54/161/287	Negative
	van der Bom et al., 1996 [61]	G1691A	112; 222	Negative
	Longstreth et al., 1998 [62]	G1691A	106; 391	Negative
	Halbmayer et al., 1997 [63]	G1691A	229; 71	Negative
	Markus et al., 1996 [64]	G1691A	180; 80	Negative
Factor VII	Nishiuma et al., 1997 [65]	R353Q	137; 83/87	Negative
	Heywood et al., 1997 [66]	R353Q	286; 198	Negative
	Corral et al., 1998 [67]	R353Q/323A2	104; 104	Negative
Factor XIII	Catto et al., 1998 [68]	Val34Leu	529; 437	Negative
β-Fibrinogen	Schmidt et al., 1998 [11]	C148T	399	Positive
	Carter et al., 1997 [12]	G448A	305; 197	Positive
	Kessler et al., 1997 [10]	G455A	227; 225	Positive
GPIa/IIa	Carlsson et al., 1999 [13]	C807T	227; 170	Positive
	Carlsson et al., 1997 [69]	HPA-5	218; 165/321	Negative
GPIbα	Gonzalez-Conejero et al., 1998 [14]	VNTR	104; 104	Positive
		HPA-2	104; 104	Positive
GPIIb/IIIa	Carter et al., 1998 [16]	P1A2	505; 402	Positive
	Ridker et al., 1997 [70]	P1A2	209; 209	Negative
	Carlsson et al., 1997 [69]	HPA-1	218; 165/321	Negative
		HPA-3	218; 165/321	Negative
PAI 1	Catto et al., 1997 [71]	4G/5G	421; 172	Negative
Prothrombin	Longstreth et al., 1998 [62]	G20210A	106; 391	Negative
	Poort et al., 1996 [72]	G20210A	104; 104	Negative
	Martinelli et al., 1997 [59]	G20210A	155; 155	Negative
	Ridker et al., 1999 [73]	G20210A	259; 1,744	Negative

GP, glycoprotein; PAI, plasminogen activator inhibitor.