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Theoretical model for the formation of a CatSper hetero-terameric channel. (a) Diagramatic representation of CatSper subunits 1–4. (b) In this model a tetrameric channel is formed via direct interaction of the coiled-coil domains. (c) In this model the channel is brought together via an auxiliary protein or proteins, interaction being mediated via the coiled-coil domains.
