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C-terminal tail in closed and open conformations. The four segments of the tail in the open conformation are shown in purple (301–315), red (316–326), purple (327–335), and red (336–350). The conformation of this segment in the ATP:PKI(5–24) ternary complex is shown in white. ATP is yellow. Tyr-330 is highlighted. Adapted from ref. 26.
