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. 1998 Jan 20;95(2):484–491. doi: 10.1073/pnas.95.2.484

Figure 3.

Figure 3

Open and closed conformations of the C subunit. The binary complex of mC and iodinated PKI(5–22) adopts an open conformation (Left). The ternary complex, rC:Mn2ATP:PKI(5–24) is closed (Right). The distances between the His-87 side chain and Thr-197 phosphate and between the Tyr-330 and the P-3 Arg of the inhibitor peptide serve as quantitative indicators for the degree of “openness.” The glycine-rich loop (residues 47–56), the linker strand (residues 121–127), and PKI(5–24) are highlighted in black.