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FISH chromosomal mapping of human TLR genes. Denatured chromosomes from synchronous cultures of human lymphocytes were hybridized to biotinylated TLR cDNA probes for localization. (A) TLR2. (B) TLR3. (C) TLR4. (D) TLR5. Assignment of the FISH mapping data (Left) with chromosomal bands was achieved by superimposing FISH signals with 4,6-diamidino-2-phenylindole-banded chromosomes (Center) (27). Analyses are summarized in the form of human chromosome ideograms (Right).
