Fig. 1.

Passive transfer of SARS hyperimmune antisera protects mice from challenge with SARS-CoV. Left-hand y-axis: Mean viral titer in lungs is expressed as log₁₀ TCID₅₀/g tissue with a lower limit of detection of 1.5 log₁₀ TCID₅₀/g, error bars represent the S.E., ^*p = 0.02 pairwise comparison of test groups to control group that received non-immune mouse serum. Right-hand y-axis: Reciprocal mean antibody titer, expressed as log₂, is the dilution of serum antibody that neutralized 100 TCID₅₀ of SARS-CoV. The lower limit of detection was ≤2, error bars represent S.E., ^**p ≤ 0.0001 pairwise comparison of test groups to control group that received non-immune mouse serum.