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. Author manuscript; available in PMC: 2007 Apr 2.
Published in final edited form as: Gene. 2006 Jan 10;365:11–20. doi: 10.1016/j.gene.2005.09.031

Fig. 1.

Fig. 1

Strategy for detection of Alu insertion polymorphisms using computational comparative genomics. The sequence of an Alu plus 100 bp flanking sequences on both ends from genome A is used to query genome B. If no perfect full-length match is found, then the two flanking sequences are joined (along with the removal of one copy of the TSDs) to query genome B again. If only a single perfect full-length match is found, then this Alu insertion in genome A is considered to be absent from genome B and thus polymorphic.