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. Author manuscript; available in PMC: 2007 Oct 1.
Published in final edited form as: Mol Endocrinol. 2006 Jun 1;20(10):2539–2547. doi: 10.1210/me.2006-0116

Fig. 3. UVB Stimulates Transcriptional Activity of CRH (A) and POMC (B) Promoters.

Fig. 3

Normal human melanocytes were transfected with a reporter gene construct driven by the sequence of human CRH promoter (−969 to +7; p-CRH-Luc) or human POMC promoter (−771 to −8; p-POMC-Luc) and with PhRL-TK (transfection efficiency control). Cells were irradiated with UVB (0–100 mJ/cm2) and lysed at the time points indicated on the figure, when activity of the promoter was measured. Data are presented as mean ± SEM (n = 3).