Table 2.
Individual tool AROC values and sensitivity data for HLA-B*3501 using binders and nonbinders from the community binding resource.
| Tool | AROC | 0.99 Specificity | 0.95 Specificity | ||||
| Rank | Sensitivity | Threshold | Rank | Sensitivity | Threshold | ||
| ARB Matrix | 0.849 | 1 | 0.242 | 12.890 | 1 | 0.422 | 296.090 |
| Bimas | 0.808 | 7 | 0.047 | 60.000 | 8 | 0.166 | 24.000 |
| NetMHC 2.0 Matrix | 0.789 | 2 | 0.137 | 32.386 | 2 | 0.336 | 28.404 |
| HLA Ligand | 0.786 | 8 | 0.043 | 162.000 | 4 | 0.237 | 145.000 |
| Rankpep | 0.769 | 5 | 0.071 | 124.000 | 3 | 0.256 | 107.000 |
| Logistic Regression | 0.764 | 11 | 0.024 | 0.655 | 11 | 0.123 | 0.259 |
| SVMHC SYFPEITHI | 0.742 | 3 | 0.118 | 0.680 | 6 | 0.204 | 0.420 |
| SVMHC MHCPEP | 0.733 | 8 | 0.043 | 1.560 | 6 | 0.204 | 1.140 |
| MHCPred (position only) | 0.692 | 6 | 0.057 | 140.600 | 9 | 0.156 | 210.860 |
| MHCPred (interactions) | 0.683 | 4 | 0.090 | 52.240 | 5 | 0.209 | 179.470 |
| Predep | 0.587 | 10 | 0.038 | -6.020 | 10 | 0.128 | -5.090 |
For details, see the caption for Table 1.