Table 5.
Performance of the heuristic-based method on all four datasets
Specificity | HLA-A*0201 (comm) | HLA-B*3501 (comm) | H-2Kd (comm) | HLA-A*0201 (lit) |
0.99 | 0.404 | 0.313 | 0.467 | 0.271 |
0.95 | 0.618 | 0.393 | 0.617 | 0.475 |
The sensitivity of the HBM is shown at 0.99 specificity and 0.95 specificity for all four of the datasets used in this study. All values were obtained using a value of 0.99 for the individual tool specificity parameter. The abbreviation "comm" refers to peptides derived from the community binding database, while "lit" refers to peptides gathered from the literature.