Table 3.
Mortality: Cox proportional hazards models between baseline characteristics and death
| Univariate analysis | Multivariate analysis | ||||
| Baseline Characteristic | No. of Deaths | Hazard ratio 95% CI | p | Hazard ratio 95% CI | p |
| Gender | |||||
| Male | 6 | 1.00 | 1.00 | - | |
| Female | 7 | 1.14 (0.38–3.40) | 0.810 | 2.78 (0.66–11.86) | 0.163 |
| Age | |||||
| < 3 yrs | 5 | 1.00 | 1.00 | - | |
| 3–5 yrs | 2 | 0.35 (0.07–1.81) | 0.210 | 1.37 (0.21–9.04) | 0.747 |
| 6–8 yrs | 3 | 0.52 (0.12–2.16) | 0.365 | 0.25 (0.02–2.93) | 0.268 |
| ≥ 9 yrs | 3 | 0.92 (0.22–3.85) | 0.908 | 2.18 (0.44–10.85) | 0.342 |
| WHO clinical stage | |||||
| Stage 1–3 | 7 | 1.00 | 1.00 | - | |
| Stage 4 | 6 | 3.01 (1.01–8.95) | 0.048* | 1.82 (0.41–8.03) | 0.430 |
| Weight (**2 missing values) | |||||
| ≥ 5 Percentile | 1 | 1.00 | 1.00 | - | |
| < 5 Percentile | 10 | 8.60 (1.10–67.15) | 0.040* | 4.96 (0.45–55.31) | 0.193 |
| CD4% (**1 missing value) | |||||
| ≥ 5% | 5 | 1.00 | - | - | |
| < 5% | 7 | 2.65 (0.84–8.34) | 0.097 | - | - |
| Tuberculosis | |||||
| Absent | 5 | 1.00 | 1.00 | - | |
| Present | 8 | 3.39 (1.11–10.37) | 0.032* | 1.08 (0.25–4.59) | 0.919 |
| Pulmonary | |||||
| Absent | 9 | 1.00 | - | - | |
| Present | 4 | 1.53 (0.47–5.01) | 0.480 | - | - |
| Extrapulmonary | |||||
| Absent | 10 | 1.00 | - | - | |
| Present | 3 | 3.06 (0.84–11.20) | 0.091 | - | - |
| Chronic gastroenteritis | |||||
| Absent | 3 | 1.00 | 1.00 | - | |
| Present | 10 | 6.69 (1.84–24.30) | 0.004* | 12.34 (1.27–119.71) | 0.030* |
| Pneumonia | |||||
| Absent | 9 | 1.00 | 1.00 | - | |
| Present | 4 | 5.23 (1.61–16.98) | 0.006* | 4.03 (0.79–20.54) | 0.094 |
| PCP | |||||
| Absent | 10 | 1.00 | 1.00 | - | |
| Present | 3 | 3.81(1.05–13.86) | 0.042* | 5.35 (0.84–33.86) | 0.075 |
| Oesophageal candidiasis | |||||
| Absent | 12 | 1.00 | - | - | |
| Present | 1 | 0.92 (0.12–7.04) | 0.932 | - | - |
| Hemoglobin | |||||
| > 10 g/dl | 5 | 1.00 | - | - | |
| ≤ 10 g/dl | 8 | 1.87 (0.61–5.73) | 0.272 | - | - |
| Primary caregiver HIV Status | |||||
| HIV negative or unknown | 10 | 1.00 | - | 1.00 | - |
| HIV positive | 3 | 0.26 (0.07–0.95) | 0.041* | 0.12 (0.02–0.88) | 0.037* |
| Primary caregiver receiving HAART at Sinikithemba | |||||
| Primary caregiver not in care | 12 | 1.00 | - | - | - |
| Primary caregiver in care | 1 | 0.13 (0.02–1.01) | 0.051 | - | - |
| Parent status | |||||
| Two parent alive | 6 | 1.00 | - | - | - |
| One parent alive | 4 | 0.92 (0.26–3.26) | 0.896 | - | - |
| Neither parent living | 3 | 0.82 (0.21–3.28) | 0.778 | - | - |