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. Author manuscript; available in PMC: 2007 Aug 22.
Published in final edited form as: Nature. 2007 Feb 7;445(7130):915–918. doi: 10.1038/nature05562

FIGURE 1.

FIGURE 1

Five ancestral populations in H. pylori. a) DISTRUCT24 plot of the proportions of ancestral nucleotides in 769 H. pylori isolates as determined by Structure V2.0 (linkage model)17. A thin line for each isolate indicates the estimated amount of ancestry from each ancestral population as five colored segments. The lines are grouped by (sub)population and ordered by ancestry. b) Neighbor joining tree (black lines) of the relationships between and diversity within five ancestral populations calculated as described2. Circle diameters are proportional to within-population genetic diversity and angles of filled arcs are proportional to the amount of ancestry attributable to each population among modern strains. scale bar: 0.01. c-g) Spatial distribution of five geographic sources of ancestral nucleotides. Dark-light gradients show clinal declines in proportions of ancestral nucleotides by distance from a geographic centre. Color-coding as in part b. AE1, AE2: ancestral Europe 1 and 2.