Table 4.
Clinical studies that investigated the accuracy of the spectral tissue Doppler E/E' for the diagnosis of acute congestive heart failure on admission before tailored therapy.
| Reference | Population study | Number of patients | Sensitivity-Specificity | Threshold value for E/E' |
| Dokainish97 | NYHA II to IV LVEF < 50% |
76 | 92% – 72% | Average E/E' > 15 |
| Dokainish97 | NYHA II to IV LVEF > 50% |
46 | 79% – 93% | Average E/E' > 15 |
| Arques98 | Acute dyspnea at rest LVEF > 45% |
70 | 80% – 94.3% 76.7% – 91.4% |
Average E/E' > 11.5 Septal E/E' > 13 |
| Arques99 | Acute dyspnea at rest LVEF > 50%, BNP 100–400 pg/ml |
34 | 88.2% – 76.5% 76.5% – 88.2% |
Average E/E' > 10.1 Septal E/E' > 13 |
| Arques100 | Acute dyspnea at rest, elderly LVEF > 50%, atrial fibrillation |
41 | 81.8% – 89.5% | Septal E/E' > 13 |
| Arques104 | Acute dyspnea LVEF > 50%, hypertension |
40 | 77.8% – 100% | Lateral E/E' > 11 |
| Huang105 | Acute dyspnea LVEF < 50% |
-* | 70.8% – 100% | Average E/E' > 16 |
| Huang105 | Acute dyspnea LVEF > 50% |
-* | 88.9% – 82.9% | Average E/E' > 11 |
BNP: B-type natriuretic peptide; LVEF: left ventricular ejection fraction;*: overall population of 92 patients.