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. Author manuscript; available in PMC: 2007 Apr 4.
Published in final edited form as: Neurotoxicol Teratol. 2006 Nov 24;29(1):57–65. doi: 10.1016/j.ntt.2006.11.007

Fig. 4.

Fig. 4

Shows DA levels in response to a natural reinforcer presented by percent change from baseline (y-axis). Figure insert describes pretreatment group as either adolescent saline, adolescent cocaine, adult saline or adult cocaine administration 3 weeks prior to microdialysis. A) DA levels in response to water and B) DA levels in response to 0.3 M sucrose. Adolescent rats pretreated with 20.0 mg/kg of cocaine have significantly higher DA levels in response to sucrose than those pretreated with saline during either adolescence or adulthood and those pretreated with cocaine as adults (p<0.05).