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. Author manuscript; available in PMC: 2007 Apr 4.
Published in final edited form as: Virology. 2006 Oct 4;358(2):384–390. doi: 10.1016/j.virol.2006.08.045

Figure 4.

Figure 4

Papilloma outgrowth after wild type CRPV, CRPVL1ATGknockout mutant and CRPV/ROPVL1 hybrid DNA challenge in four EIII/JC inbred rabbits. Four sites/per animal were challenged with each constructs respectively (N=16). The CRPVL1ATGko mutant induced significantly larger papillomas when compared with those induced by wild type CRPV (P<0.05, unpaired student t test). Significantly smaller and fewer papillomas were induced by CRPV/ROPVL1 hybrid infection when compared to those induced by wild type CRPV (P<0.01, unpaired student t test).