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. 2007 Mar 8;26(7):1924–1933. doi: 10.1038/sj.emboj.7601639

Figure 3.

Figure 3

Reversed synaptic plasticity in JP-DKO cerebellum. LTP was induced in JP-DKO mice with conjunctive stimulation (stimuli of both PFs and CFs at 1 Hz for 5 min), which induces LTD in DHE mice. (A) (left) Changes in PF-EPSC amplitude before and after the conjunctive stimulation. The amplitude was normalized by the mean value observed for 10 min before the conjunctive stimulation. (right) Sample traces immediately before (1) and 30 min after the conjunctive stimulation (2). (B) Average PF-EPSC amplitude during the 21–30 min period after the conjunctive stimulation. Mean±s.e.m. **P<0.01, significantly different from the value for JP-DHE mice. Data were obtained from 8- to 10-week-old mice.