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. 2007 Apr 6;3(4):e49. doi: 10.1371/journal.ppat.0030049

Figure 2. Mtb Proteins Containing Domains Homologous to the B. subtilis Alternative Sigma Factor Regulators SpoIIAA and SpoIIAB.

Figure 2

Four of the Mtb homologs of the B. subtilis SpoIIAB (anti–sigma factor) or SpoIIAA (anti-anti–sigma factor) encode proteins that have been shown to regulate SigF or SigH. Rv0941c contains both types of domain, and Rv1364c contains both domains as well as an RsbU-like, Ser/Thr phosphatase domain. Three of the seven anti-anti–sigma factor domains are preceded by a Ser/Thrrich N-terminal extension (blue). This extension in Rv0516c contains the site of PknD phosphorylation.