Table 1. Axon guidance defects in animals with altered Tsc-Rheb-Tor signaling.

(Percent of optic lobes affected)
						Incorrect Terminations
3rd instar larvae	Thick LP	Gaps in LP	LP Peaked	Long R7/8	Gaps in Med.	Above LP	Below LP	In Med.
Tsc129 (n = 58)	70	41	7	5	31	45	52	72
Ptendj189 (n = 38)	24	100	79	63	29	58	68	95
Rheb3M2/26.2 (n = 22)	68	55	0	0	41	32	18	36
TorA948V (n = 12)	17	17	0	8	0	0	17	33
S6kl-1 (n = 49)	29	41	2	0	2	10	14	4
TorA948V Tsc129 (n = 14)	21	29	0	0	7	7	0	0
S6kl-1 Tsc129 (n = 23)	65	83	0	0	70	43	17	43
wild-type +Rap (n = 80)	19	13	0	0	9	21	14	13
Tsc129 +Rap (n = 60)	76	54	2	6	59	46	71	63
40-hour pupae		Pathfinding Defects		De-fasciculation Defects		Termination Layer Defects
Tsc129 (n = 60)		100		100		100
elav-Gal4>UAS-Rheb (n = 23)		83		43		39
Ptendj189 (n = 73)		25		30		8
Rheb26.2 (n = 80)		36		3		19
S6kl-1 (n = 32)		28		9		25
TorA948V (n = 20)		35		0		10
TorA948V Tsc129 (n = 25)		40		4		16

*Tsc1²⁹, Pten^dj189, and Rheb^26.2 are eyFLP mosaics; all others are mutants. LP - lamina plexus; Med. - medulla; Rap - rapamycin