TABLE 2.
Predicted and Observed Distribution of Radicals Trapped on the Components of DNA
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| DNA components at different Γ | No. bound e− (′) | Bound e− (%) | Initial hole distribution (%) | Initial e− adduct distribution (%) | Predicted initial free radical distribution (%) | Neglect outer shell free radical (%) | Renormalize (%) | Observed free radical distribution (%) | Calculated free radical distribution (%) |
| Γ = 2.5 | |||||||||
| Bases | 48 | 35 | 17 | 50 | 67 | 67 | 67 | 89 | 89 |
| Sugar-phosphate | 63 | 45 | 23 | 0 | 23 | 23 | 23 | 11 | 11 |
| Solvent shell,a Γ ≤ 10 | 28 | 20 | 10 | 0 | 10 | 10 | 10 | ||
| Sum | 139 | 100 | 50 | 50 | 100 | 100 | 100 | 100 | 100 |
| Γ = 7.5 | |||||||||
| Bases | 48 | 27 | 13 | 50 | 63 | 63 | 63 | 88 | |
| Sugar-phosphate | 63 | 35 | 18 | 0 | 18 | 18 | 18 | 12 | |
| Solvent shell,a Γ ≤ 10 | 68 | 38 | 19 | 0 | 19 | 19 | 19 | ||
| Sum | 179 | 100 | 50 | 50 | 100 | 100 | 100 | 100 | |
| Γ = 11.5 | |||||||||
| Bases | 48 | 23 | 11 | 50 | 61 | 61 | 63 | 89 | 88 |
| Sugar-phosphate | 63 | 30 | 15 | 0 | 15 | 15 | 15 | 11 | 12 |
| Solvent shell,a Γ ≤ 10 | 88 | 42 | 21 | 0 | 21 | 21 | 21 | ||
| Solvent shell, Γ > 10 | 12 | 6 | 3 | 3 | b | ||||
| Sum | 211 | 100 | 50 | 50 | 100 | 97 | 100 | 100 | 100 |
| Γ = 15.0 | |||||||||
| Bases | 48 | 20 | 10 | 50 | 60 | 60 | 65 | 88 | |
| Sugar-phosphate | 63 | 26 | 13 | 0 | 13 | 13 | 14 | 12 | |
| Solvent shell,a Γ ≤ 10 | 88 | 37 | 18 | 0 | 18 | 18 | 20 | ||
| Solvent shell, Γ > 10 | 40 | 17 | 8 | 8 | b | ||||
| Sum | 239 | 100 | 50 | 50 | 100 | 92 | 100 | 100 | |
| Γ = 22.5 | |||||||||
| Bases | 48 | 16 | 8 | 50 | 58 | 58 | 70 | 90 | 90 |
| Sugar-phosphate | 63 | 21 | 11 | 0 | 11 | 11 | 13 | 10 | 10 |
| Solvent shell,a Γ ≤ 10 | 88 | 29 | 15 | 0 | 15 | 15 | 18 | ||
| Solvent shell, Γ > 10 | 100 | 33 | 17 | 17 | b | ||||
| Sum | 299 | 100 | 50 | 50 | 100 | 83 | 100 | 100 | 100 |