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Cytotoxicity of SS scFv-PE38 on human cancer cell lines
| Cell line | Origin | K1 reactivity by IF | IC50 ng/ml |
|---|---|---|---|
| A431 | Epidermoid carcinoma | − | 450 |
| A431 K5 | Mesothelin-transfected A431 | ++++ | 0.5 |
| ATAC-4 | p55-transfected A431 | − | 400 |
| AGS | Gastric adenocarcinoma | ++ | 6 |
| N87 | Gastric adenocarcinoma | ++ | 6 |
| A1847 | Ovarian adenocarcinoma | ++/het | 16 |
| JD38 | Burkitt’s lymphoma | − | >1,000 |
| Raji | Burkitt’s lymphoma | − | >1,000 |
| HUT 102 | T cell leukemia | − | >1,000 |
IF, immunofluorescence.
