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Time course of the effect of NOR-1 on MUC5AC promoter activity. A549 cells were transfected with vehicle or MUC5AC promoter. Transfected cells were stimulated with 0.1 mM of NOR-1 and the transcriptional activity of MUC5AC promoter was measured at 10, 20, 40, 60 and 120 min. after exposure. ** significantly different, p < 0.01, from MUC5AC promoter-alone transfection group.
