Table 2.
Hazard ratios for various outcomes for women aged 50-79 years using hormone replacement therapy
| Outcome | Hazard ratio (95% CI) for combined oestrogen progestogen | Hazard ratio (95% CI) for oestrogen only |
|---|---|---|
| Stroke (mainly ischaemic) | 1.41 (1.07 to 1.85)9 | 1.39 (1.10 to 1.77)10 |
| Breast cancer (final results) | 1.24 (1.01 to 1.54)11 | 0.77 (0.59 to 1.01)12 |
| Deep vein thrombosis | 1.95 (1.43 to 2.67)13 | 1.47 (1.06 to 2.06)14 |
| Coronary heart disease (final results) | 1.24 (1.00 to 1.54)15 | 0.77 (0.59 to 1.01)16 |
| Dementia (women >65 years) | 2.05 (1.21 to 3.48)17 | 1.49 (0.83 to 2.66)18 |
| Gall bladder disease and procedure | 1.59 (1.20 to 1.97)19 | 1.67 (1.35 to 2.06)19 |
| Hip fracture | 0.66 (0.45 to 0.98)9 | 0.61 (0.41 to 0.91)10 |
| Total fracture | 0.76 (0.69 to 0.85)9 | 0.70 (0.63 to 0.79)10 |
| Colorectal cancer | 0.63 (0.43 to 0.92)9 | 1.08 (0.75 to 1.55)10 |
| Total mortality | 0.98 (0.82 to 1.18)9 | 1.04 (0.88 to 1.22)10 |