Figure 5.
Morphological and histological characteristics of mammary glands in adult PR-A transgenic mice. Whole-mounts (A–C) and histology (D–H) of mammary glands from young (10–14 weeks old) control PR-A transgene-negative (A and D) and PR-A transgenic mice (B, C, and E–H) are shown. In B and C, open arrows show thick ducts and solid arrow shows clustered buds at the tip of ducts. In G, arrow shows an indistinct epithelial–stromal boundary, and in H, arrow shows disorganized masses of cells at the tip of a duct.