Table 5.
Segregation of FRAXE intermediate alleles from carrier parents
| Selection | Null hypothesis, p = .5
|
ML estimate, p̂ | Equivalent meioses
|
|||
|---|---|---|---|---|---|---|
| ML score, Up | Information, Kpp | χ12 | Carrier | Total | ||
| Complete–retarded child | 12 | 48 | 3.00 | .750 | 9 | 12 |
| Complete–other tested children* | 0 | 64 | 0.00 | .500 | 8 | 16 |
| Mother carrier | −2 | 12 | 0.33 | .333 | 1 | 3 |
| Father carrier–all children | 0 | 64 | 0.00 | .500 | 8 | 16 |
Retarded vs. other heterogeneity χ12 = 1.71.
Includes single selection with proband omitted.