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. 1998 Jan 20;95(2):730–734. doi: 10.1073/pnas.95.2.730

Figure 1.

Figure 1

(A) Genomic map of the region in the tcp gene cluster affected by two independent transposon insertions (arrowheads). The BclI sites show the extent of the deletion in the ΔtcpP strain. (B) Comparison of the tcpP and tcpH genes to psaE and psaF from Yersinia pestis (20) and toxR and toxS from V. cholerae (6, 7). Arrows indicate the direction and sizes of the ORFs. Sequences encoding hydrophobic regions representing potential transmembrane domains are shown in black. (C) Proposed membrane topology of ToxR, ToxS, TcpP, and TcpH. Carboxyl (C) and amino (N) termini of the proteins are indicated.