Table 3.
Crude and adjusted RR of scoring < 80 points in the Social Competence scale at 4 years of age in relation to in utero exposure to HCB [coefficient (95% CI)].
| Exposure | Unadjusted (n = 377) | Adjusteda (n = 377) | Adjusted for other OCsb (n = 377) | Menorca cohortb (n = 329) |
|---|---|---|---|---|
| HCB category | ||||
| Referencec | 1 | 1 | 1 | 1 |
| 0.5–0.99 ng/mL | 1.16 (0.62–2.18) | 1.40 (0.68–2.87) | 1.77 (0.83–3.79) | 1.84 (0.82–4.11) |
| 1–1.49 ng/mL | 1.04 (0.48–2.29) | 1.47 (0.59–3.62) | 1.83 (0.72–4.69) | 1.51 (0.52–4.35) |
| ≥ 1.5 ng/mL | 2.88 (1.39–5.97)* | 4.04 (1.76–9.58)* | 5.63 (2.13–14.88)* | 6.18 (2.06–18.50)* |
| HCB (ng/mL)d | 1.52 (1.05–2.22)* | 1.79 (1.15–2.76)* | 2.10 (1.30–3.40)* | 2.18 (1.28–3.74)* |
a
Adjusted for age, cohort, sex, maternal education, paternal education, tobacco and alcohol exposure, maternal age in years, and type and duration of breast-feeding (see “Population and Methods”).
b
Adjusted for same variables above and PCBs, p,p′-DDE and p,p′-DDT.
c
Reference group: < 0.5 ng/mL.
d
Natural log-transformed HCB concentration.
*
p < 0.05.