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. Author manuscript; available in PMC: 2007 Dec 1.
Published in final edited form as: Stem Cells. 2006 Aug 24;24(12):2703–2713. doi: 10.1634/stemcells.2006-0217

Figure 5. Lymphoid progenitors rebounding from chemotherapy are, like fetal progenitors, in active cell cycle.

Figure 5

After 90 hours of 5-FU treatment, mice were given BrdU i.p. and in drinking water for 6 hours. ABM was recovered at 96 h and the purified 5-FU LinGFP+c-kit+ lymphoid progenitors and control ELP were stained with anti-BrdU to examine proliferation rates (A), or stained for Hoechst 33342 and Pyronin Y (B). In parallel, BrdU was given to pregnant mice for six hours and FL E14 ELP were analyzed. Telomerase activity was measured quantitatively in FL E14 ELP, ABM ELP and ABM 5-FU LinGFP+c-kit+ by Real-Time PCR (C). The graph shows median values (attomol/μl) with bars representing standard errors. *p=0.025.