Figure 7.

Bcl-2 increases unstimulated Ca²⁺ influx and basal [Ca²⁺]_c. (A and B) Cells were suspended in a Ca²⁺-free medium, and 1 mM Ca²⁺ was added to the medium after 5-min baseline recording. (A) Typical experiments showing [Ca²⁺]_c elevations in control and Bcl-2-transfected cells without cellular stimulation. (B) Typical experiments showing [Ca²⁺]_c elevations in control and Bcl-2-transfected cells after TG stimulation. (C) Basal [Ca²⁺]_c of cells maintained in Ca²⁺-free medium or in Ca²⁺-containing medium; mean ± SEM of four independent experiments. (D) Statistical analysis of experiments as shown in A. (E) Statistical analysis of experiments as shown in B.