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. 2000 Feb;156(2):567–575. doi: 10.1016/S0002-9440(10)64761-X

Figure 2.

Figure 2.

Overall survival of patients with esophageal SCC as indicated by staining for u-PA in cancer cells (A), u-PA in fibroblasts (B), and u-PAR in cancer cells (C). D: Group A (n = 11) had neoplastic cells that stained for only u-PA and had u-PA-negative fibroblasts. Group B (n = 12) comprises patients whose cancer cells were positive for only u-PAR and whose fibroblasts were positive for u-PA. Patients in Group C (n = 23) had cancer cells negative for both u-PA and u-PAR and fibroblasts negative for u-PA. As shown in A, the prognosis of patients with u-PA-positive cancer cells is significantly poorer than that of patients whose cancer cells are u-PA-negative. D illustrates that group A has a significantly worse prognosis than do groups B and C.