Table 2.
Genetic Alterations in Sarcomatous and Gliomatous Components of Gliosarcomas
| Patient no. | Biopsy | Area | Genetic alteration |
|---|---|---|---|
| 210 | 2nd | S | p53 mutation (codon 151, CCC→TCC) |
| G | p53 mutation (codon 151, CCC→TCC) | ||
| 213 | 1st | S | p16 deletion |
| G | — | ||
| 214 | 1st | S | p16 deletion |
| G | p16 deletion | ||
| 215 | 1st | S | PTEN mutation (codon 107, GAT→GCT) |
| G | PTEN mutation (codon 107, GAT→GCT) | ||
| 218 | 1st | S | PTEN mutation (codon 274, TGG→TGA) |
| G | PTEN mutation (codon 274, TGG→TGA) | ||
| 220 | 1st | S | CDK4 amplification, MDM2 amplification |
| G | CDK4 amplification, MDM2 amplification | ||
| 223 | 1st | S | — |
| G | — |
S, sarcomatous component; G, gliomatous component; —, no genetic alterations.